Searchable abstracts of presentations at key conferences in endocrinology

ea0099rc7.5 | Rapid Communications 7: Endocrine-related Cancer | ECE2024

Fibroblast-mediated modulation of GI-NETs: Implications for drmg response and tumor invasion

Malavasi Eleonora , Toffoli Lara , Dainotto Marilyn , Ditsiou Angeliki , Gagliano Teresa

Introduction: The intricate interplay between fibroblasts and cancer cells significantly contributes to cancer invasion, extracellular matrix (ECM) modulation, and the development of drmg resistance. This study delves into understanding the specific influence of fibroblasts on Gastro-Intestinal neuroendocrine tumor (GI-NET) cell lines.Materials and Methods: Utilizing GOT1 and COLO320 cell lines, we incorporated Normal Human Dermal Fibroblasts (NF) in our...